ABSTRACT
Vernet syndrome associated with varicella zoster virus (VZV) has been rarely reported. The diagnosis is established based on typical symptoms such as dysphagia, hoarseness, and unilateral difficulty in neck movement. Lack of skin lesions is common and makes it harder to consider VZV infection. A 53-year-old woman presented with left neck pain, dysphagia, hoarseness, and headache, with an erythematous vesicle on her neck. Laryngoscopy revealed paralysis of her left-soft palate and left-vocal cord. Upon cerebrospinal fluid (CSF) examination, her white blood cell (WBC) count, protein levels, glucose levels, and VZV antibody titer were elevated; moreover, VZV-DNA was detected. Magnetic resonance imaging (MRI) showed no sign of brain tumor, aneurysm or fracture. The patient was diagnosed with Vernet syndrome associated with VZV infection, having presented with a skin lesion involving the cervical segment.
Subject(s)
Female , Humans , Middle Aged , Aneurysm , Brain Neoplasms , Cerebrospinal Fluid , Chickenpox , Deglutition Disorders , Diagnosis , Glucose , Headache , Herpesvirus 3, Human , Hoarseness , Laryngoscopy , Leukocytes , Magnetic Resonance Imaging , Neck , Neck Pain , Palate , Paralysis , SkinABSTRACT
No abstract available.
Subject(s)
Forehead , Hyaluronic Acid , Imaging, Three-Dimensional , Pilot ProjectsABSTRACT
Neck wrinkles commonly develop owing to the aging process. However, recently, the number of patients with neck wrinkles has been increasing. Also, an increasing number of young patients have presented with this condition, possibly because of the effect of the head-down posture that they adopt when using their computer or smartphone. We report two cases of young adults with a prominent neck wrinkle. In case 1, a 29-year-old woman with a neck wrinkle was treated with six intradermal radiofrequency (RF) procedures. Her neck wrinkle was significantly improved with the RF treatment. In case 2, a 32-year-old woman with a wrinkle and generalized light brownish tiny papules on the neck was treated with three intradermal RF procedures simultaneously with 30% glycolic acid peeling. Her wrinkle and skin tone were improved dramatically. We conclude that intradermal RF has a considerable efficacy for reducing neck wrinkles.
Subject(s)
Adult , Female , Humans , Young Adult , Aging , Neck , Posture , SkinABSTRACT
No abstract available.
ABSTRACT
The potential role of topical valproate (VPA) in hair regrowth has been recently suggested. However, safety reports of VPA as a topical formulation are lacking. Therefore, in the present study, we investigated whether VPA causes skin irritation in humans. We first performed a cell viability test and showed that VPA did not exhibit toxicity toward HaCaT keratinocytes, fibroblasts, and RBL-3H mast cells. We then performed clinical patch test and skin irritation test through transdermal drug delivery with the help of microneedle rollers. No significant findings were obtained in the clinical patch test. In the skin irritation test, only 1 patient showed erythema at 1 hr, but the irritation reaction faded away within a few hours. Erythema and edema were not observed at 24 hr. We concluded that VPA has minimal potential to elicit skin irritation. Therefore, we consider that VPA can safely be applied to human skin.
Subject(s)
Humans , Cell Survival , Edema , Erythema , Fibroblasts , Hair , Keratinocytes , Mast Cells , Patch Tests , Skin , Valproic AcidABSTRACT
Papular elastorrhexis is a rare disorder, possibly a form of multiple elastic tissue nevi. The disorder typically presents as several asymptomatic, firm, nonfollicular, 1- to 5-mm-diameter, and well-demarcated white papules. It predominantly appears on the trunk, including the chest, abdomen, back and shoulders, upper extremities, and, rarely, thighs. Histologically, it is characterized by substantial fragmentation or nearly complete loss of elastic tissue in the reticular dermis. We report a 37-year-old female with popular elastorrhexis, which developed on a rare site, only dorsal aspect of the hand and foot with no involvement of the proximal extremities.